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Gene Therapy

New findings in gene therapy described by T.J. Harris and co-researchers

Published in Medicine and Law Weekly, March 12th, 2010

A report, 'Tissue-specific gene delivery via nanoparticle coating,' is newly published data in Biomaterials. "The use of biomaterials for gene delivery can potentially avoid many of the safety concerns with viral gene delivery. However, the efficacy of polymeric gene delivery methods is low, particularly in vivo," scientists in the United States report.

"One significant concern is that the interior and exterior composition of polymeric gene delivery nanoparticles are often coupled, with a single polymer backbone governing all functions from biophysical properties of the polymer/DNA particle to DNA condensation and release. In this work we develop...

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