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Mental Health Business Week

Susan Hasty, Publisher

Table of Contents . . . January 12th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Mental Health Business Week | Other Publications

Maxygen, Inc. - 5HTIA serotonin receptor agonists suppress P. falciparum growth

Azienda Osped San Camillo Forlanini - Intragastric balloon effective for weight loss in obese patients

University of Pittsburgh - Early hormone replacement is fundamental to limiting cognitive decline

University of Pittsburgh - Gadd45a contributes to p53 stabilization in response to DNA damage

University of Portsmouth - Short-term meningioma cultures express key matrix metalloproteinases

University of South Florida - Managing older chemo patients involves preventing pharmacologic complications

University of Szeged - A whole genome screen reveals 33 genes associated with multiple sclerosis

University of the Sacred Heart, Rome - Apolipoprotein E is a nerve recovery and neovascularization intermediary

University of Tokyo - CO poisoning is due to ROS affecting neurons; hypothermia can reduce the damage

University of Toronto - Genetics research could spawn further creation of targeted, nontoxic therapies

University of Toronto - New understanding of why brain cells die after stroke will lead to new treatments

University of Turin - Response to ghrelin administration decreased in human obesity

Bioject Medical Technologies - Phase I study completed comparing needle-free system to traditional syringe

University of Uppsala Hospital - Neuropsychological assessment useful as complement to neurological exam

Vanderbilt University - Antiretroviral treatment increases oxidative stress

Washington University - Major differences between pediatric, adult meningeal tumors reported

Wayne State University - Scientists provides new insights into basis of diabetic neuropathy

Whitehead Institute - Mad cow mechanism may be integral to storing memory

Yale University - Brain area that regulates emotions is smaller in manic-depressive people

Yale University - Protein tyrosine phosphatases in nervous system reviewed

Zhejiang University - Conotoxin MVIIA and thioredoxin fusion protein has analgesic activity

Bristol-Myers Squibb Co. - Lexicon enters neuroscience alliance for drug development

Carnegie Mellon University - Individuals have consistent physiological responses to stressors; immune changes

Catholic University of Louvain - The cytokine interleukin-1beta is highly expressed in SIDS brains

Center University of Orsay - Huntingtin signaling pathways regulate toxicity in Huntington disease

Children's Hospital, Westmead - Changes in the noradrenergic system underlie anorexia nervosa risk

Chiron Corp. - Experts: Antiquated flu vaccine system needs updating

CHU Purpan, Toulouse - The effect of estradiol on airway reactivity is dose related

CHU Vaudois - SLURP-1 is an epidermal neuromodulator; its gene is mutated in Mal de Meleda

NPS Pharmaceuticals, Inc. - Company begins clinical trial in migraine, appoints chief medical officer

Colorado Wound Care - Diabetic patients believe protective footwear lack value

Creutzfeldt Jakob Disease - First case of mad cow found in U.S.

CSIC, Cajal Institute - The enzyme aromatase helps estradiol to protect the brain from degeneration

CSIRO Biomedical Devices - New device may help premature babies

Environmental Toxins - Low-mercury choices for fish a challenge

Forest Laboratories, Inc. - Lexapro receives FDA approval for generalized anxiety disorder

German Cancer Research Center - Neuroblastoma-derived sulfhydryl oxidase reverses resistance to apoptosis

German Cancer Research Center - Soluble factors role in glioma invasion may lead to new therapies

Gynecological Exams - Patient education, respect key to reducing women's gyn exam anxiety

Hungarian Academy of Sciences - Increased nitric oxide is early sign of premature aging in diabetes

Saegis Pharmaceuticals, Inc. - CNS-focused biopharmaceutical company announces new vice president

International Epidemiology Inst., Rockville - Cancer incidence seen near former nuclear materials facilities in Pennsylvania

Jagiellonian University - IL-10 release following intracerebral hemorrhage varies depending on hemisphere

Johns Hopkins University - MeCP2, the mutated transcription factor in Rett syndrome, alters nerve synapses

Johns Hopkins University - O-GlcNAc plays role in diabetes, cancer, and neurodegeneration

Korea Institute of Radiological & Med. Science - Oxidative stress-induced apoptosis mediated by ERK1/2 phosphorylation

Kumamoto University - VLDL/chylomicron plays role in amyloid formation

Kyung Hee University - Embolization may be the optimal way to treat pelvic congestion syndrome

Ludwig Maximilians Universitat, Munchen - Possible new human prion disease described

M.D. Anderson Cancer Center - Capecitabine may result in clinical and radiographic tumor responses

Mahidol University - Exercise during pregnancy improves spatial learning in newborn animals

Welch Foods, Inc. - Concord grape juice improved memory, neuromotor skills in animal study

Managed Care Interface - Study shows controlled-release paroxetine decreases risk of discontinuation

Massachusetts General Hospital - Gender and familial associations are linked to ADHD and major depression

Max Planck Institute - Molecular chaperones protect parkin from oxidative stress inactivation

Mayo Clinic - A rapid serological assay can identify amyloidogenic transthyretin variants

Medical University of Lodz - A whole genome screen reveals five genes associated with multiple sclerosis

Mental Health - Study: Cohabiting better for men's mental health; marriage better for women's

Nagoya University - Liposomal delivery offers clinical gene therapy for brain tumors

NE Ohio University - Estrogen protects against methamphetamine-induced neurological insult

New York Eye Cancer Center - High-frequency ultrasonography plays novel role in eye tumor diagnosis

Newcastle General Hospital - DJ-1 gene polymorphism not linked to Parkinson disease

Second University of Naples - Wolf isotopic response can be granuloma annulare at herpes zoster wound site

Northwick Park Hospital, Harrow - Quality of life after surgical treatment of head and neck cancers reviewed

Nutra Pharma Corp. - Acquisition to advance treatment of viral diseases and neurological disorders

Oita University - Neuroprotection due to HSP induction may occur with geranylgeranylacetone

Okayama University - Glutamate neurotoxicity may be blockable by a calcineurin-inhibiting peptide

Oregon Health Sciences University -  Ginkgo biloba prevents memory deficits in Alzheimer disease animal models

Osaka University - Interneuronal synapse formation, actin restructuring involves cadherins, nectins

Paladin Laboratories, Inc. - Low temperatures in Canada contribute to morbidity and mortality

Pasteur Institute - Extracellular regulated kinases 1/2 are prion protein signaling targets

Pediatrics - West Virginia has shortage of child psychiatrists

Prana Biotechnology Limited - Alzheimer disease treatment slows progression of cognitive decline in study

SkyePharma, PLC - Study: Patients treated with Paxil CR are less likely to discontinue therapy

St. Jude Children's Hospital - Usefulness of FISH in morphologically ambiguous gliomas examined

Stanford University - Pediatric renal graft loss linked to non-adherence, teenage, mental illness

Stanford University - VEGF is a prerequisite for exercise-induced hippocampal neurogenesis

Substance Abuse - Individuals with eating disorders more likely to abuse alcohol and drugs

Texas Tech University - Researchers find low levels of perchlorate in evaporated milk samples

Tokyo Metropolitan Neurology Hospital - Neurons in Duchenne, myotonic dystrophy have excess non-cholinergic synapses

Tottori University - Intraoperative GH measurement helps boost safety of secondary transnasal surgery

U.S. Food & Drug Administration - Drug carcinogenicity determined using structural similarity and E-state index

U.S. Food & Drug Administration - galE gene in campylobacters linked to Guillain-Barre syndrome

Afferent Corporation - Device company's neurotechnology improves foot sensation in diabetics

U.S. Natl. Inst. of Environmental Health Sciences - Some CpG G:C-A:T transitions may be caused by smoking

ULB Erasme - Minocycline activates the tetracycline-responsive promoter in treated cells

Univ of Alabama, Birmingham - Hepatitis C virus infection may encourage the formation of diabetic amyotrophy

Univ. of Alabama, Birmingham - Oncolytic viruses used as vectors for treatment of malignant gliomas

Univ. of British Columbia - Neutralizing antibodies to IFN beta-1b therapy for relapsing-remitting MS may affect outcome

Univ. of California, Berkeley - Single gene plays key role in neural tube defects

Univ. of California, Irvine - Down syndrome study reveals possible method for detecting initial stages of AD

Univ. of California, Los Angeles - Shyness can be deadly

Univ. of California, Riverside - Rapid botulinum toxin type B microsensor developed

Univ. of Complutense, Madrid - Bulimia nervosa patients and normal eaters have similar 5-HTT gene mutations

Alkermes, Inc. - New treatment for schizophrenia may further relieve symptoms of stable patients

Univ. of Texas SW Medical Center - LDL receptor-related protein controls blood-brain barrier permeability

Univ. of Texas SW Medical Center - Piccolo proteins pique neurons

Univ. of Western Ontario - Vascular changes prevail in disorders that host chronic neuroinflammation

Universit Paris-Sud - Nerve degeneration in familial amyloid polyneuropathy studied

Universitat Heidelberg - Niemann-Pick disease type C caused by disturbed lipid transport

Universitats Augenklinik Essen - Thyroid-associated ophthalmopathy can be treated by anti-inflammatories, surgery

University of Alberta - TRAIL triggers apoptosis in human malignant glioma cells

University of Auckland - Crystal structure of M. tuberculosis MshB protein characterized

University of Bonn - Epigenetic silencing of HIC-1 may play role in most medulloblastomas

University of Edinburgh - TNF-alpha may play an early role in the malignant transformation of liver cells

Axonyx, Inc. - Scope of Phenserine trial; sub-study to include brain scans

University of Florida - Strong families enjoy most support from those who find it difficult

University of Groningen Hospital - Novel hyaluronan-based biomaterials support nerve repair

University of Innsbruck - Gamma-aminobutyric acid receptor expression increased in epilepsy

University of Kiel - Sacral neuromodulation beneficial for patients with neurogenic urinary retention

University of Kuopio - New MRI contrasts discern response to gene therapy in rodent glioma models

University of Madrid - Early antiretroviral treatment is neuroprotective in vertically infected children

University of Milan - Neurons of dorsal motor vagal nucleus show hypoxia-related marker in SIDS brains

University of Murcia - Microangiogenesis facilitates parkinsonism

University of Paris - Innervation may be early target in type 1 diabetes

University of Parma - Creutzfeldt-Jakob disease can occur as a result of an insertion in the PRNP gene

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