Published in Mental Health Business Week, March 12th, 2005
"Activation of phosphatidylinositol 3-kinase (P13-K) is considered to be a key event upon stimulation of cells with growth factors. Akt is known to be a downstream target of P13-K when it is activated by nerve growth factor (NGF). NGF induces cell differentiation of PC12 cells as indicated by neurite outgrowth," wrote Y. Kim and colleagues, Korea Institute Science & Technology.
"In order to investigate the role of PI3-K/Akt in NGF-induced differentiation of PC12 cells, we generated cells ectopically expressing constitutively...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Mental Health Business Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.