Griffith University, Australia
Post-ischemic murine hearts show selective oxidative events are limited by adenosine
Published in Mental Health Business Week, September 30th, 2006
According to a study from Australia, "Despite the general understanding that ischemia-reperfusion (I/R) promotes oxidant stress, specific contributions of oxidant stress or damage to myocardial I/R injury remain poorly defined. Moreover, whether endogenous 'cardioprotectants' such as adenosine act via limiting this oxidant injury is unclear."
"We characterized effects of 20 min ischemia and 45 min reperfusion on cardiovascular function, oxidative stress and damage in isolated perfused mouse hearts (with glucose or pyruvate as substrate), and examined...
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