Fragile X Syndrome Genetics
Scientists at Massachusetts Institute of Technology discuss research in Fragile X syndrome genetics
Published in Mental Health Business Week, September 1st, 2007
Research findings, "Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice," are discussed in a new report. According to a study from the United States, "Fragile X syndrome (FXS), the most commonly inherited form of mental retardation and autism, is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) gene and consequent loss of the fragile X mental retardation protein. Despite growing evidence suggesting a role of specific receptors and biochemical pathways in FXS pathogenesis, an effective therapeutic method has not been developed."
"Here, we report that abnormalities in FMR1 knockout (KO) mice, an animal model of...
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