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Eating Disorders

Reports on eating disorders findings from Institute of Animal Science provide new insights

Published in Mental Health Business Week, September 8th, 2007

Data detailed in "Signals generating anorexia during acute illness" have been presented. According to recent research from Switzerland, "Anorexia is part of the body's acute-phase response to illness. Microbial products such as lipopolysaccharides (LPS), which are also commonly used to model acute illness, trigger the acute-phase response and cause anorexia mainly through pro-inflammatory cytokines."

"LPS stimulate cytokine production through the cell-surface structural molecule CD14 and toll-like receptor-4. Cytokines ultimately change neural activity in brain areas controlling food intake and energy balance. The blood-brain barrier endothelial cells (BBB EC) are an...

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