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Schizophrenia Genetics

Scientists at University of Minho, Life and Health Sciences Research Institute target schizophrenia genetics

Published in Mental Health Business Week, September 8th, 2007

New research, "Transthyretin: no association between serum levels or gene variants and schizophrenia," is the subject of a report. According to a study from Braga, Portugal, "It has been proposed that schizophrenia results from an environmental insult in genetically predisposed individuals. Environmental factors capable of modulating transcriptional activity and their carriers could link the genetic and environmental components of schizophrenia."

"Among these is transthyretin (TTR), a major carrier of thyroid hormones and retinol-binding protein (RBP). Retinoids and thyroid hormones regulate the expression of several genes, both during development and in the adult...

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