Schizophrenia
Researchers from Albany Medical College, Medical College provide details of new studies and findings in the area of schizophrenia
Published in Mental Health Business Week, October 20th, 2007
Data detailed in 'Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia' have been presented. "A neonatal ventral hippocampal lesion (NVHL) induces behavioral and physiological anomalies mimicking pathophysiological changes of schizophrenia. Because prefrontal cortical (PFC) pyramidal neurons recorded from adult NVHL rats exhibit abnormal responses to activation of the mesocortical dopaminergic (DA) system, we explored whether these changes are due to an altered DA modulation of pyramidal neurons," scientists in the United States report.
"Whole-cell recordings were used to examine the...
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