Stanford University Medical Center

Stanford Study Recruits Twins for Pharmacogenetic Study of Opiates

Published in Mental Health Business Week, November 29th, 2008

Opiates such as morphine and codeine are the primary prescription medication for pain relief, but just how well these drugs work varies significantly from patient to patient. And no one really knows why.

Certain patients may require 10 times the amount of opiates, also known as narcotics, to get the same level of pain relief as others. Side effects such as nausea or sedation can be debilitating to some, while nonexistent for others. Addiction potential also varies from patient to patient.

"We rely heavily on narcotics as the cornerstone medication for the relief of moderate to severe pain," said Martin Angst, MD, associate professor of anesthesia at...

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Source: Mental Health Business Week (2008-11-29)

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