Anxiety Disorders

Reports outline anxiety disorders study findings from P.G. Unschuld and colleagues

Published in Mental Health Business Week, February 13th, 2010

"Glutamate decarboxylase (GAD) is the rate limiting enzyme for conversion of glutamic acid to gamma-aminobutyric acid (GABA). The GAD 65 kDa isoform is encoded by the gene GAD2 and is mainly expressed in synaptic terminals," investigators in Munich, Germany report.

"It serves as an apoenzyme, which shows enhanced availability in situations of stress, responding to short-term demands for GABA. We analyzed 18 single nucleotide polymorphisms (SNPs) in the GAD2-gene region for associations with psychiatric diagnosis and behavioral inhibition (BI) derived from the personality traits neuroticism and extraversion as defined by the Eysenck Personality Questionaire (EPQ). A...

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Source: Mental Health Business Week (2010-02-13)

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