University of Groningen Hospital
Novel hyaluronan-based biomaterials support nerve repair
Published in Mental Health Law Weekly, January 12th, 2004
"We investigated possible cytotoxic effects, biocompatibility, and degradation of a hyaluronan-based conduit for peripheral nerve repair. We subjected the conduits to an in vitro fibroblast cytotoxicity test and concluded that the conduits were not cytotoxic. Subsequently, we implanted the conduits subcutaneously in rats, in order to investigate tissue reactions and biodegradation," scientists in Netherlands report.
"Initially, a fibrin matrix was formed around the material, while the surroundings were relatively quiet. Macrophages (MO) migrated to the conduits and formed giant cells next to...
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