Universidad Complutense
Candida albicans strain protects against systemic candidiasis
Published in Mental Health Law Weekly, June 26th, 2004
According to recent research from Spain, "A low virulent Candida albicans mutant, CNC13, deleted in the mitogen activated protein (MAP) kinase HOG1 was used to immunize BALB/c mice. Hog1p is essential for the oxidative stress and hyperosmolarity responses. Several doses and immunization procedures were employed. The protection capacity of the different sera generated was analyzed in a murine model of systemic candidiasis."
"Using a proteomic approach (two-dimensional gel electrophoresis followed by Western blotting), we were able to distinguish two...
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