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Stockholm University

COMT gene polymorphism correlates with adult and old age memory function

Published in Mental Health Law Weekly, October 30th, 2004

COMT gene polymorphism correlates with adult and old age memory function.

According to published research from Sweden, "variation in memory performance is to a large extent explained by genes. In the prefrontal cortex, the catechol O-methyltransferase (COMT) gene is essential in the metabolic degradation of dopamine, a neurotransmitter implicated in cognitive functions. The present study examined the effect of a polymorphism in the COMT gene on individual differences and changes in memory in adulthood and old age."

"Tests assessing episodic and semantic memory were administered to 286 men (initially aged 35-85 years) from a random sample of the...

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