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Mental Health Law Weekly

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Tottori University



Cholinergic dysfunction stronger in Lewy body dementia than in Alzheimer disease



December 17th, 2005

Compared to Alzheimer patients, cholinergic dysfunction is more pronounced in Lewy body dementia.

"Clinicopathophysiological differences between dementia with Lewy bodies (DLB) and Alzheimer disease (AD) remain obscure," neurologists in Japan explained.

In a recent study, T. Kai and colleagues at Tottori University sought "to determine whether characteristic findings of electroencephalogram (EEG) power and coherence in DLB and a differential pathophysiological mechanism of quantitative EEG existed between DLB and AD."

"The group consisted of 15 patients with AD or DLB and 12 age-matched controls," the scientists noted. "Original...


Source: Mental Health Law Weekly (2005-12-17)

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