RIKEN Brain Science Institute
ASCL1 may be associated with Parkinson disease
Published in Mental Health Law Weekly, December 17th, 2005
"We previously identified frequent deletion/insertion polymorphisms in the 20-Ala homopolymer stretch of PHOX2B (PMX2B), the gene for a transcription factor that plays important roles in the development of oculomotor nerves and catecholaminergic neurons and regulates the expression of both tyrosine hydroxylase and dopamine beta-hydroxylase genes."
"An association was detected between gene polymorphisms and overall schizophrenia, and more specifically, schizophrenia with ocular misalignment,"...
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