Mental Health Law Weekly
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Johns Hopkins University School of Medicine
Scientists find that stimulating prostaglandin brain cell receptors may protect against cell damage
December 17th, 2005
A study by Johns Hopkins scientists has revealed that stimulating brain cell receptors for certain hormone-like chemicals in brain cells called prostaglandins can protect the cells from amyloid-beta-peptide 42 (amyloid-beta1-42), a compound that has been linked to brain cell death and Alzheimer disease (AD). Prostaglandin E2 (PGE2 ) is produced via the action of the COX-2 enzyme, which can contribute to brain injury. In spite of the negative effects of COX-2, ongoing studies have shown that PGE2 can actually provide some protection against brain cell death by binding to various PGE2 receptors. ...
Source: Mental Health Law Weekly (2005-12-17)
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