Mental Health Law Weekly
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Karolinska Institute
HTR2C linkage disequilibrium is associated with BMI and serum leptin levels in humans
December 17th, 2005
HTR2C linkage disequilibrium is associated with body mass index and serum leptin levels in mice and humans. "The occurrence of obesity, eating disorders, and related diseases has increased in many parts of the world. Given that few strong genetic factors have been found, it is clear that these are complex multifactorial diseases. The serotonin receptor 2C, a member of the 5-HTergic system, has been implicated in the control of phagia and obesity," scientists in Sweden report. S. McCarthy and colleagues at the Karolinska Institute in Stockholm conducted "a detailed investigation of linkage disequilibrium (LD) within and between the HTR2C promoter and...
Source: Mental Health Law Weekly (2005-12-17)
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