Mental Health Law Weekly
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University of Georgia
Melanocortins and leptin play key role in adipose tissue apoptosis and fat deposition
December 17th, 2005
Melanocortins and leptin play an important role in adipose tissue apoptosis and fat deposition. According to a recent review from the United States, "Leptin has a wide range of effects on physiological functions related to the regulation of body energy balance. Many of leptin's effects are mediated through neuropeptide-containing neurons and neuropeptide receptors in the hypothalamus." "The melanocortin system includes both agonist (alpha-melanocyte stimulating hormone, alpha MSH) and antagonist peptides (agouti related peptide, AGRP). Increased melanocortin receptor stimulation following leptin administration plays an important role in...
Source: Mental Health Law Weekly (2005-12-17)
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