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Mental Health Law Weekly

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University of California, Irvine



Neural stem cells differentiate and promote locomotor recovery after spinal cord-injury



December 17th, 2005

Neural stem cells differentiate and promote locomotor recovery after spinal cord-injury.

According to a study from the United States, "We report that prospectively isolated, human CNS stem cells grown as neurospheres (hCNS-SCns) survive, migrate, and express differentiation markers for neurons and oligodendrocytes after long-term engraftment in spinal cord-injured NOD-scid mice.

"hCNS-SCns engraftment was associated with locomotor recovery, an observation that was abolished by selective ablation of engrafted cells by diphtheria toxin. Remyelination by hCNS-SCns was found in both the spinal cord injury NOD-scid model and myelin-deficient shiverer...


Source: Mental Health Law Weekly (2005-12-17)

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