Mental Health Law Weekly
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Brown University, Providence
Decreasing cancer-suppressing protein activity increases lifespan in fruit fly model
December 17th, 2005
Too much production of the p53 protein shortens lifespan. Not enough can cause cancer. New research, headed up by Brown University biologist Stephen Helfand, shows that the health benefits of this protective protein can be harnessed - and longer life can be achieved - when its activity is decreased in the neurons of fruit flies. These findings, published in Current Biology, offer the first evidence that p53 can play a positive role in aging. Fruit flies can live significantly longer, and remain healthy, when activity of the fly version of the tumor-suppressing protein p53 is reduced in nerve cells. Published in Current Biology, the...
Source: Mental Health Law Weekly (2005-12-17)
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