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Schizophrenia Association of Great Britain, Bangor

Calcium-independent cytosolic PLA2 genes may be linked to schizophrenia

Published in Mental Health Law Weekly, December 17th, 2005

Recently published research from England has chronicled a genetic study of two calcium-independent cytosolic PLA2 genes in schizophrenia.

"The present study detected 9 single nucleotide polymorphisms (SNPs) at the PLA2G4C and PLA2G6 loci among 240 Chinese parent-offspring trios of Han descent."

"Of these 9 SNPs, 5 showed highly polymorphic in the Chinese population," wrote Y.Q. Yu and colleagues, Schizophrenia Association of Great Britain.

"They were then applied as genetic markers to test the genetic association of these two calcium-independent cytosolic PLA2 genes with schizophrenia. The transmission disequilibrium test (TDT)...

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