Alcoholism
New findings from Veterans Affairs Medical Center describe advances in alcoholism
Published in Mental Health Law Weekly, October 27th, 2007
Researchers detail in 'Implication of altered proteasome function in alcoholic liver injury,' new data in alcoholism. According to recent research published in the World Journal of Gastroenterology, "'The proteasome is a major protein-degrading enzyme, which catalyzes degradation of oxidized and aged proteins, signal transduction factors and cleaves peptides for antigen presentation. Proteasome exists in the equilibrium of 26S and 20S particles."
"Proteasome function is altered by ethanol metabolism, depending on oxidative stress levels: low oxidative stress induces proteasome activity, while high oxidative stress reduces it. The proposed mechanisms for...
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