Mental Retardation

Reports outline mental retardation study results from N. Lemeur et al

Published in Mental Health Law Weekly, March 6th, 2010

According to recent research from France, "Over the last few years, array-comparative genomic hybridisation (CGH) has considerably improved our ability to detect cryptic unbalanced rearrangements in patients with syndromic mental retardation. Molecular karyotyping of six patients with syndromic mental retardation was carried out using whole-genome oligonucleotide array-CGH."

"5q14.3 microdeletions ranging from 216 kb to 8.8 Mb were detected in five unrelated patients with the following phenotypic similarities: severe mental retardation with absent speech, hypotonia and stereotypic movements. Facial dysmorphic features, epilepsy and/or cerebral malformations were also...

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Source: Mental Health Law Weekly (2010-03-06)

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