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Dementia Therapy

Reports from University of Pittsburgh, Western Psychiatric Institute describe recent advances in dementia therapy

Published in Mental Health Law Weekly, March 13th, 2010

Investigators publish new data in the report 'Serotonin transporter triallelic genotype and response to citalopram and risperidone in dementia with behavioral symptoms.' "The risk/benefit ratio of pharmacotherapy for behavioral symptoms of dementia is questionable: second-generation antipsychotics are poorly tolerated, and the efficacy of alternative treatments, for example, selective serotonin-reuptake inhibitors (SSRIs), is uncertain. Biomarkers of treatment response may improve this risk/benefit ratio," scientists in the United States report.

"The length polymorphism of the serotonin transporter promoter gene (5-HTTLPR/SLC6A4) may moderate tolerability of SSRIs and...

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