Mental Health Weekly Digest
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Bipolar Disorder
Seroquel combined with mood stabilizer may improve mania symptoms
June 28th, 2004
Patients with mania associated with bipolar disorder receiving Seroquel (quetiapine fumarate) adjunct therapy in combination with lithium or divalproex achieved significantly greater rates of response and remission from manic episodes than patients receiving lithium or divalproex alone, according to a study published in Bipolar Disorders. Results from this randomized, double-blind, placebo-controlled study showed that at 3 weeks, 54.3% of patients treated with Seroquel in combination with lithium or divalproex achieved a response [defined as greater than or equal to 50% YMRS (Young Mania Rating Scale) improvement], compared with 32.6% treated with lithium or...
Source: Mental Health Weekly Digest (2004-06-28)
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