Neuroscience
Rare human sequence variants do not impact vesicular monoamine transporter 2
Published in Mental Health Weekly Digest, December 13th, 2004
According to recent research from the United States, "the extent to which genetic variation in a population contributes to phenotypic variation depends on the frequency of sequence polymorphisms and the effect of these polymorphisms on function. The frequency of polymorphisms might also reflect the severity of their effects on function."
"We therefore examined the effect of very rare single nucleotide polymorphisms (SNPs) on the activity of the vesicular monoamine transporter 2 (VMAT2, SLC18A2), a gene implicated in neuropsychiatric disease," J. Burman and colleagues,...
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