Neurology
Electroconvulsive depression therapy raises rat hippocampal BDNF
Published in Mental Health Weekly Digest, March 20th, 2006
"Electroconvulsive therapy is considered to be an effective treatment for severe depression," according to pharmacologists in Japan, who previously showed that "the antidepressant-like effects of tricyclic antidepressants in the rat forced swim test are blocked by repeated treatment with adrenocorticotropic hormone (ACTH)."
"In the present study," B. Li and colleagues at Ehime University "investigated the effect of repeated electroconvulsive stimuli on the forced swim test and on brain-derived neurotrophic factor (BDNF) protein levels in ACTH-treated...
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