Mental Health Weekly Digest
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HIV/AIDS Dementia
HIV-infected opiate abusers with ApoE4 allele may have increased dementia risk
August 28th, 2006
Antioxidants protect against the neurotoxity of HIV Tat plus morphine in HIV-infected opiate abusers with the Apoliprotein E4 allele. "Human immunodeficiency virus (HIV) infection continues to rise in drug-abusing populations and causes a dementing illness in a subset of individuals. Factors contributing to the development of dementia in this population remain unknown," scientists in the United States report. According to J. Turchan-Cholewo and colleagues at the University of Kentucky, "We found that HIV-infected individuals with the E4 allele of Apolipoprotein E (ApoE) or history of intravenous drug abuse had increased oxidative stress in the...
Source: Mental Health Weekly Digest (2006-08-28)
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