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Mental Health Weekly Digest

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Parkinson Disease



Nicotine may protect against brain damage that occurs in Parkinson disease



August 28th, 2006

New research suggests that nicotine treatment protects against the same type of brain damage that occurs in Parkinson disease.

The research was conducted in laboratory animals treated with MPTP, an agent that produces a gradual loss of brain function characteristic of Parkinson. Experimental animals receiving chronic administration of nicotine over a period of six months had 25% less damage from the MPTP treatment than those not receiving nicotine.

This protective effect may explain the lower incidence of Parkinson disease among smokers. The results also suggest that nicotine may be useful as a potential therapy in the treatment of early-stage...


Source: Mental Health Weekly Digest (2006-08-28)

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