Mental Health Weekly Digest
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Schizophrenia
Polymorphism interaction does not influence susceptibility to schizophrenia
August 28th, 2006
Recently published research from South Korea has reported on an interaction analysis between 5-HTTLPR and TNFA-238/-308 polymorphisms in schizophrenia. "This study investigated the potential interaction between the polymorphisms of serotonin transporter gene (SLC6A4, a 44 base pair insertion/deletion in the promoter region, 5-HTTLPR) and tumor necrosis factor-alpha gene (TNFA; -238G/A and -308G/A polymorphisms) on the development of schizophrenia, as well as the interaction of the three polymorphisms in relation to symptomatology, family history, onset age and antipsychotic treatment response," wrote C.U. Pae and colleagues, Catholic University of Korea. ...
Source: Mental Health Weekly Digest (2006-08-28)
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