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Attention Deficit Hyperactivity Disorder

Gene Variant Is Associated With Brain Anatomy, Clinical Course of ADHD

Published in Mental Health Weekly Digest, August 20th, 2007

A variant of the dopamine receptor gene may be associated with attention-deficit/hyperactivity disorder (ADHD) and with thinner tissue in areas of the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the Archives of General Psychiatry, one of the JAMA/Archives journals.

ADHD is among the most heritable of neuropsychiatric disorders, according to background information in the article. Several genes have been identified as possibly associated with the condition. One of the most frequently cited is a polymorphism or different type of the dopamine D4 receptor gene (DRD4)...

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