Prion Disease
New findings from Case Western Reserve University describe advances in prion disease
Published in Mental Health Weekly Digest, August 18th, 2008
In this recent report published in the journal Annals of Neurology, researchers in the United States conducted a study "To report a novel prion disease characterized by distinct histopathological and immunostaining features, and associated with an abnormal isoform of the prion protein (PrP) that, contrary to the common prion diseases, is predominantly sensitive to protease digestion. Eleven subjects were investigated at the National Prion Disease Pathology Surveillance Center for clinical, histopathological, immunohistochemical, genotypical, and PrP characteristics."
"Patients presented with behavioral and psychiatric manifestations on average at 62 years,...
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