New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College

N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets

Published in Mental Health Weekly Digest, August 25th, 2008

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

Their breakthrough research, featured as the cover story in a recent issue of Molecular Cell, describes the precise molecular and biochemical structure of drug targets known as neurotransmitter-sodium symporters (NSSs), and how cells use them to enable neural signaling in the brain. A second study,...

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Source: Mental Health Weekly Digest (2008-08-25)

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