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New York University

Memory study on mice offers new insights into understanding autism, NYU, Baylor scientists conclude

Published in Mental Health Weekly Digest, December 22nd, 2008

Researchers at New York University's Center for Neural Science and the Baylor College of Medicine have identified a protein that when removed from mice results in behaviors that are akin to those with autism and obsessive-compulsive disorders. Their findings, which appear in the latest issue of the journal Neuron, may enhance our understanding of these and other neurological disorders.

The protein FKBP12, found in both humans and mice, is known to regulate mTOR, an enzyme involved in synaptic plasticity, or the ability of the neurons to change the collective strength of their connections with other neurons. Learning and memory are believed to result from changes in...

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