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Schizophrenia

Data from Peking University Provide New Insights into Schizophrenia

Published in Mental Health Weekly Digest, May 23rd, 2011

2011 MAY 23 -- According to recent research from Beijing, People's Republic of China, "Synaptic hypothesis of schizophrenia suggests that alterations of synaptic transmission and neuronal connectivity might be core feature of schizophrenia. STON2 participates in synaptic vesicle protein recognition and neural endocytosis."

"To explore the association of STON2 with schizophrenia, 11 single nucleotide polymorphisms (SNPs) were examined in 768 Chinese Han schizophrenia cases and 1347 Chinese Han controls. The results showed that three SNPs had strong association with schizophrenia, two exonic SNPs (rs2241621: allelic P = 0.0005; rs3813535: allelic P = 0.0078)...

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