Autoimmune Oophoritis
Synthetic Peptides Proposed as Immunogens
Published in Monoclonal Antibodies Weekly, February 23rd, 2000
"To circumvent autoimmune oophoritis after immunization with zona pellucida (ZP) glycoproteins, synthetic peptides encompassing B-cell epitope(s) and devoid of oophoritogenic T-cell epitopes as immunogens have been proposed," stated C.K. Govind and colleagues, National Institute Immunology, Gamete Antigen Laboratory, India. "In this study bonnet monkey ZP glycoprotein-B (bmZPB) was expressed as polyhistidine fusion protein in Escherichia...
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