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Pathogenesis

Impairment of Object and Action Naming in AD

Published in Neurological Diseases and Disorders Weekly, December 14th, 1998

Both conceptual and lexical retrieval systems for objects, but only conceptual systems for actions, are impaired during the pathogenesis of Alzheimer's disease, according to a recent study.

D. Williamson et al. administered measures of object naming and action naming to matched groups of 10 patients with Alzheimer's disease (AD) and 10 normal, control subjects ("Object and Action Naming in Alzheimer's Disease," Cortex, 1998;34(4):601-610).

"AD patients were impaired in both object and action naming, with object naming impaired to a significantly greater extent than action naming. This difference remained after controlling for the effects of word...

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