Emory University

Progress is expected to lead to specific antihypertensive treatments

Published in Nursing Home and Elder Business Week, November 28th, 2004

A recent report provides an update on the topic of reactive oxygen species in hypertension.

According to the report from the United States, "Hypertension is associated with an elevation of reactive oxygen species (ROS) and frequently also with an impairment of endogenous antioxidant mechanisms. Experimental manipulation of the redox state in vivo shows that ROS can be a cause of hypertension."

B. Lassegue and K.K. Griendling of Emory University explained, "During the development of the disease, ROS are generated by endogenous sources, notably the NADPH oxidase enzyme family and uncoupled nitric oxide synthase, due to a mutual reinforcement between...

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Source: Nursing Home and Elder Business Week (2004-11-28)

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