Concordia University, Montreal

Candida albicans hyphal development studied, role of cyclin Cln3p revealed

Published in Nursing Home and Elder Business Week, March 27th, 2005

According to recent research from Canada, cyclin Cln3p links G₁ progression to hyphal and pseudohyphal development in Candida albicans.

"G₁ cyclins coordinate environmental conditions with growth and differentiation in many organisms. In the pathogen C. albicans, differentiation of hyphae is induced by environmental cues but in a cell cycle-independent manner.

"Intriguingly," wrote C. Bachewich and colleagues, Concordia University, "repressing the G₁ cyclin Cln3p under yeast growth conditions caused yeast cells to arrest in G₁ , increase in size, and then develop into hyphae and...

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Source: Nursing Home and Elder Business Week (2005-03-27)

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