Chang Gung Memorial Hospital, Keelung
Researchers' work adds to cardiology body of knowledge
Published in Nursing Home and Elder Business Week, June 19th, 2005
Study 1: Inhibition of NF-kappa B activation can attenuate ischemia/reperfusion-induced contractility impairment via decreasing cardiomyocytic proinflammatory gene upregulation and matrix metalloproteinase expression.
According to recent research published in the Journal of Cardiovascular Pharmacology, "Following cardiopulmonary bypass (CPB) and cardiac global ischemia and reperfusion, proinflammatory genes are upregulated, and nuclear factor (NF)-kappaB is involved in this regulation. We studied whether inactivation of NF-kappa B could decrease myocardial...
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