University of Texas, U.S.
Oral cancers that metastasize are likely to overexpress lymphangiogenesis factor.
Published in Nursing Home and Elder Business Week, September 24th, 2006
"Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential role of podoplanin in certain tumor cells," scientists writing in the journal Cancer report.
"The purpose of the current study was to determine the role of podoplanin in head and neck squamous cell carcinoma (HNSCC). Podoplanin expression was analyzed in 35 patients with HNSCC including 16 oral tumors and 19 hypopharyngeal tumors by immunohistochemical analysis and the association between the podoplanin expression...
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