Published in Nursing Home and Elder Business Week, May 10th, 2009
"However, whether animal age or jet lag influences the d-gal-induced aging process has not been investigated. To clarify these issues, ICR male mice were given a daily injection of d-gal (500 mg/kg bw) for 7 wks. d-gal-treatment caused a significant decrease only in the transcript level of Cat gene in the 6-wk-old mice, whereas it significantly reduced the expression of Cat and Sod1 genes and of Cat, Gpx1, Sod1 and Sod2 genes in the 12- and 22-wk-old group, respectively, suggesting that d-gal induced...
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