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Anti-Candida Antibodies

Highly specific antibodies to cell wall beta-glucans are in normal human sera

Published in OBGYN and Reproduction Week, June 23rd, 2003

Some normal human antibodies found in commercial pooled gamma globulin are highly specific for Candida cell wall beta-glucan.

Published research from Japan covered the development of "a protocol to obtain a soluble Candida spp. beta1, 3-glucan (CSBG) by sodium hypochlorite (NaClO) oxidation and subsequent dimethyl sulfoxide (DMSO) extraction. CSBG is composed mainly of beta-1,3 and beta-1,6-glucosidic linkages with a small amount of branching.

"Antibody to beta-glucan is generally difficult to produce. In the present study, the specificity of the human sera to CSBG was examined by ELISA. Using CSBG coated plates, sera from normal human...

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