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Toxoplasmosis

Sulfadiazine presents risk of kidney failure during pregnancy

Published in OBGYN and Reproduction Week, January 5th, 2004

Sulfadiazine given to pregnant women for toxoplasmosis can result in kidney stones and failure if not approached properly.

"Obstructive renal failure is a rare but serious complication of pregnancy. Although most cases are due to extrinsic compression, renal tract obstruction can also be due to intraluminal precipitation of sulfadiazine prescribed for maternofetal toxoplasmosis," researchers in France report.

"The diagnosis is suggested by clinical history, ultrasound (radiolucent stones situated anywhere in the renal tract) and especially analysis of the urine pellet (wheat sheaf formation of yellowish crystals). Urinary drainage by double J stent...

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