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Neuroscience
Young malnourished rats model the neurodevelopmental changes of schizophrenia
March 15th, 2004
Young malnourished rats model the neurodevelopmental changes of schizophrenia. "Epidemiological studies suggest that prenatal malnutrition increases the risk of developing schizophrenia. Animal models indicate that prenatal protein deprivation (PPD) affects many aspects of adult brain function. We tested the hypothesis that PPD in rats would alter prepulse inhibition (PPI), which is an operational measure of sensorimotor gating that is deficient in schizophrenia patients," researchers in the United States report. "Additionally, we examined dopaminergic and glutaminergic receptor binding in the striatum and hippocampus, which have been suggested to...
Source: OBGYN & Reproduction Week (2004-03-15)
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