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Pain Medicine
SD(+)-ketamine and racemic ketamine have similar effects on uterine blood flow
March 15th, 2004
SD(+)-ketamine and racemic ketamine have similar effects on uterine blood flow. "Ketamine could be a useful maternal analgesic in obstetric surgery, as it might avoid the need for opioid administration and associated side effects in the newborn. Racemic ketamine passes the placental barrier and has oxytocin-like properties but does not seem to affect uterine blood flow (UBF). S(+)-ketamine was recently approved for clinical use, but its effects on UBF have not been evaluated," scientists writing in the journal Anesthesia and Analgesia report. "Therefore, we studied the effects of S(+)-ketamine on maternal and fetal hemodynamic variables....
Source: OBGYN & Reproduction Week (2004-03-15)
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