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OBGYN & Reproduction Week

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Preeclampsia



Neurokinin B relaxes isolated human placental resistance vessels



March 15th, 2004

Neurokinin B relaxes isolated human placental resistance vessels.

According to recent research from Canada, "placental neurokinin B (NKB) was recently identified as the causative agent in preeclampsia, a condition characterized by increased maternal and feto-placental vascular resistance. We hypothesized that NKB should constrict placental resistance vessels. Placentas were obtained from normotensive pregnancies."

"Immediately after delivery, stem villous arteries (300 micrometer diameter, 1.2 mm long) were dissected from macroscopically normal tissue in cold HEPES-physiological salt solution (PSS), mounted on a wire myograph system, and bathed in...


Source: OBGYN & Reproduction Week (2004-03-15)

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