Stem Cell Research
Mechanisms controlling primordial germ cell proliferation in females explored
Published in OBGYN and Reproduction Week, April 18th, 2005
According to a recent report from Italy, "Strict control of cell proliferation and cell loss is essential for the coordinated functions of different cell populations in complex multicellular organisms.
"Oogenesis is characterized by a first phase occurring during embryo-fetal life and in common with spermatogenesis, during which mitotic proliferation of the germline stem cells, the primordial germ cells (PGC), prevails over germ cell death. The result is the formation of a relatively high number of germ cells depending on the species, ready to enter sex specific...
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