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Polycystic Ovarian Syndrome

Study finds orlistat and metformin equally effective for treatment of PCOS

Published in OBGYN and Reproduction Week, April 18th, 2005

Results of a study by endocrinologists indicate that orlistat and metformin are equally effective for treatment of polycystic ovarian syndrome.

V. Jayagopal and colleagues, University of Hull, North Humberside, U.K., evaluated and compared "the effect of treatment with orlistat vs. metformin on the hormonal and biochemical features of patients with polycystic ovarian syndrome (PCOS)."

According to their report, "Twenty-one Caucasian women with PCOS [mean(±SEM) age 27±0.9 years and body mass index 36.7±3.3 kg/m2] participated in this prospective, randomized, open-labeled study. All subjects had an 8-week run-in period...

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