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Breast Cancer

Researchers describe findings in breast cancer studies

Published in OBGYN and Reproduction Week, May 23rd, 2005

Breast cancer research advances have been reported from the United States and Spain.

Study 1: 5F 203 (2-(4-Amino-3-methylphenyl)-5-fluoro-benzothiazole) induces NF-kappa B activity in drug-sensitive human breast cancer MCF-7 cells.

According to recent research from the United States, "5F 203 potently inhibits MCF-7 breast cancer cell growth in part by activating the aryl hydrocarbon receptor (AhR) signaling pathway. Ligands for the AhR (i.e. dioxin) have also been shown to modulate the NF-kappaB signaling cascade, affecting physiological processes such as cellular immunity, inflammation, proliferation and survival."

"The objective...

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